I also have this problem. GTX 580 with the latest 320 beta drivers. Running in 2560x1600 with all settings on max. I had this happen in each of the four beta weekends as well. Filed 5 bug report tickets about it (once per beta and now in open beta too). Would be awesome if this gets fixed!
I am playing max settings, 2560x1600 resolution and also cannot turn the bloom down. It is way too high at 100% and is very noticeable in Protector's Enclave where I almost needed sunglasses to run around :P
Same, mousewheel will not zoom in or out, except in inspect mode. Even if you change the keybinds to something else you still cannot zoom outside of inspect mode. Hopefully a bug and not a feature... Also, the slider for camera max zoom does not work. I suspect this is linked to zoom not working.