I've just been able to launch it on Windows 10 by selecting Options (top right on the launcher) and ticking Safe Mode. It seems to work okay, although the graphics seem lower resolution - no idea what else Safe Mode does, but at least I'm in...
I had problems launching the game client in Windows 10, but I just tried the compatibility wizard on the game client and reverted it back to Windows 8. It seems to be working fine again at the moment (touch wood!).
Yes, there is a bug. Unless you disable the alarm in the first room you can't complete vital stages further on, but it doesn't let you go back and disable it later.
Me too! Tried dropping the mission and then accepting it again when offered, and the same Bird of Prey stuck in an asteroid shooting at me, but I can't target it. I thought it was just me!