Zhentil Keep! (That counts as a city, right?) Ran some delicious infiltration-style campaigns there against the Zhentarim battling their efforts around the Moonsea, which was always my favourite area to set stories in.
Ab-so-lutely! One of my biggest issues with mmos is the lack of constant endgame stuff that you can duo or solo. Foundry content will hopefully fill the gap. (As well as let me relive my glory days and/or youth as a 2nd and 3rd ed DM xD)