On one of my alts, I've been trying to remove a Staff of Flowers artifact from a secondary slot, but every time I try to unequip it, replace it with another artifact, or discard it using the options menu I get the error message "You cannot unequip this item while it is on cooldown." Opened a support ticket.
It's behaving just the artifact in this post from the PC bug forums way back in 2017.
https://www.arcgames.com/en/forums/neverwinter/#/discussion/1236018/i-cannot-unequip-siege-masters-war-horn-from-my-secondary-artifact-slotUpdate: Here is a video of what I'm dealing with.
https://youtu.be/NHtM1lDR9oA?si=mVTmry6k0GX-ZVJa