Thanks to the popularity of Marvel Comics' X-Men series, and the movies and television shows spawned from them, many players of CO and other supers RPGs want to play superheroes with a "mutant" background. Marvel has long used mutants as a metaphor for racism, as they suffer persecution at the hands of frightened "normal humans." The official Champions Universe doesn't feature the kind of widespread anti-mutant paranoia so often displayed in Marvel's universe. To most people on Champs Earth genetic mutation is just one source of super powers, and mutants are viewed as no better or worse than other superhumans. However, there definitely is a minority of people who do hold such fears; and for CO role players who'd enjoy that sort of angsty background for their characters, one official group is particularly willing and able to exploit those fearful people, and mold them into a force dangerous to all mutants, and any other superhumans who would stand in support of them.
To date there's been no PnP source book dedicated to the Institute for Human Advancement (IHA). One was planned before the severe downsizing of Hero Games several years ago, but AFAIK there are no current plans to publish one. Not a lot of information has appeared in other books, and what there is is scattered; but collectively it provides enough potential for some intriguing plot uses for the IHA in CO. So I thought players might find it useful if I collected it.
The core info about the Institute appears in Champions Universe
. While the current edition of that book is for the Sixth Edition of the Hero System, the previous Fifth Edition book includes some significant material relevant to the IHA which wasn't reprinted. Other small but valuable data are mentioned in Champions Universe: News Of The World, Champions Villains
Vols. 1 & 2, Millennium City, Sharper Than A Serpent's Tooth, Teen Champions, Vibora Bay,
and VIPER: Coils Of The Serpent