The support Neverwinter has for Surround resolutions (3x monitors) is pretty nice. The ability to move around most of the UI elements makes it completely playable. With that said, there are a few things that can't be moved, always appearing offscreen. I've included a picture with 3 screenshots to demonstrate:
http://imgur.com/UYnikPq
Image 1:
NPC vendor inventory can't be moved, or position isn't remembered.
Image 2:
a: Quest dialogue screen (far left) can't be moved or position isn't remembred.
b: Level Up notification (far right) can't be moved or position isn't remembered.
Image 3:
Helpful tips (left center) can't be moved or position isn't remembered.
Miscellaneous:
Celestial coin purchase menu is positioned midway between the left and center monitor. The position isn't remembered when it's moved.