Not true, althought you can use Xpadder - there is the ability to "bind" keys. There is a whole thread dedicated to this in the Controls section of the Forum. (if the threads still there). Within it were the Keybind files you could download, along with pictures of the controllers with the button layout; also instructions on how to install the Keybind setup. Something like a /load slash command but can't remember which. I used it for a while but preferred the Keyboard.
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Found it, wasn't too hard.
http://forums.startrekonline.com/showthread.php?t=91705