I can't seem to find any info on what any abilities "activation 0/none listed, 0.5, and 1 second" means and relates to specifically?
In orbit of ESD or K7 etc for example, when i click or hit a keybind for any abil, the abil activates instantly or no matter how fast or slow(how long/sustained) u press click or key it it seems however in combat often times you click or keybind an abil and it wont activate as in it's lit up, u click or key it, it shadows, then relights as in it didn't activate, many times even.
Does this mean that activation time (x) only counts when in combat/red alert mode or is it lag issue or ...what???

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I think most of what you are seeing is some sort of anti-spam global cooldown though. The only times I have experienced this sort of thing were of course the worst times, panic and try to hit all your buttons at once and only 1/3 of them are accepted...