If you switch from STO (fullscreen) to Desktop and open a browser to read something, then switching back to STO doesn`t work, because STO seems to be only a overlay of the browser and if you click something in STO the browser gets focus again and you have to switch back to STO. This bug exists since BETA. It`s not really a problem (so it wasn`t fixed yet) but it just seems cheap.
Also, on Nvidia cards, if your second monitor is on the same graphics card as the STO client, then tabbing over will often cause a memory overflow crash.
Comments
What OS are you running?