I've been having this problem for almost a year now. When I start up Arc, it asks me to put the install disc in drive E for about 5 times and then it kind of works. When I try clicking anything in Arc I still get prompted to put the install disc in drive E once or twice and then it does what I wanted it to do. It has interfered with my playing PWI, though that problem seems to have resolved itself for now. Or at least I hope it has. Is there anything I can do to get Arc and PWI to work properly again?